Key dates

  • Applications open in Sapphire: 3 September 2025
  • UQ R&I NOI close: 21 January 2026
  • Minimum data requirements in Sapphire: 5pm ACT time 21 January 2026
  • Applications due to UQ R&I: 21 January 2026
  • Applications close: 5pm ACT time 4 February 2026

Overview

This grant opportunity will provide financial assistance to support medical research and medical innovation projects that develop novel approaches to reduce treatment toxicity and adverse effects of brain cancer treatment for patients, to minimise the short- and/or long-term negative impacts for patients.

Applicants should propose research that:

  • Measures the negative impacts of brain cancer treatments.
  • Aims to improve the quality of life for people affected by brain cancer.
  • Is innovative, interdisciplinary, collaborative and translational.
  • Empowers and champions early to mid-career researchers (EMCRs), ensuring their meaningful involvement and robust support.
  • Where possible, involves health care services, including Aboriginal and Torres Strait Islander community-controlled health organisations, regional rural and remote health care services.
  • Where possible, leverages existing research initiatives and infrastructure. Examples of this include, but are not limited to, the Zero Childhood Cancer program and the Australian Brain Cancer Registry.

There is no minimum grant amount and the maximum amount available for a single grant is $2.0 million.

EMCR eligibility requirement

For applications to this grant opportunity, 30% or more of the CI team must be Early to Mid-Career Researchers. An EMCR is defined as an individual who is within ten years of their PhD award date, excluding career disruptions. CIs who are not part of the above EMCR quota are not required to hold a post-graduate qualification.

Note that the PhD award date is defined as the date an individual’s PhD thesis is passed (not the date of conferral).

How to Apply

Step 1: Internal Notice of Intent (NOI) 

All researchers intending to submit an MRFF application are required to submit an internal Notice of Intent. NOIs will be collated centrally and distributed to Faculties and Institutes in order to provide maximum support to the UQ research community.

Submit UQ Notice of Intent

Step 2. Sapphire updates and scheme reading

  • Register for Sapphire and update your full profile 'My Profile and CV'. All Chief Investigators (CI) and Associate Investigators (AI) will need to have an active Sapphire account. Any team members without a Sapphire account should request one as early as possible. The NHMRC require at least three working days to create new Sapphire accounts. 
  • Download guidelines and application templates from GrantConnect. Familiarise yourself with the key MRFF, NHMRC and UQ documentation (see below). 

Step 3. Completing the application

  • Log into Sapphire and complete the application. Sections of the application will validate as they are completed.
  • Ensure all required data is entered into the application before the Minimum Data deadline (see Key dates above). Applications that do not meet this deadline will not be able to proceed.

Step 4. UQ R&I internal review and feedback

  • Ahead of internal review, ensure all online components are complete and valid in Sapphire and CIA has initiated the Certification process. Application errors will be signalled and can be corrected during the Certification stage.
  • To initiate internal review, email the UQ Research Office at mrffgrants@research.uq.edu.au with your completed MRFF Funding Application Certification form (below).
  • UQ Research Office will review your application and provide you with feedback as requested in NOI (eligibility & compliance; refinement; or content grantscraft).

Step 5. Final submission

  • When your application is complete and fully compliant, the UQ Research Office will submit the application to the NHMRC through Sapphire.

Letters of Support

UQ Letters

Most MRFF applications administered in Sapphire will not require a letter of support from UQ. This is usually only necessary if UQ is committing cash to the project.

We ask that UQ researchers submit draft letters for signing to us no later than two weeks before the external closing date. We strongly recommend working with your local school/institute research professionals to complete this process.

Partner Letters

We encourage applicants to provide drafts of partner letters of support for review by the Research office before organising their final signature to ensure eligibility and compliance. A template partner letter of support is provided below.

Non-UQ Lead Applications

  • The administering organisation should provide you with a draft letter of support. We recommend you work with your local research support to complete the letter. 
  • Complete and sign an MRFF Funding Application Certification form (see below), and get it countersigned by your Head of School/Institute.
  • Submit both to mrffgrants@research.uq.edu.au, along with evidence for any additional co-contributions.

Readership and research support

Before applying, we recommend you:

Key documents

Before applying, please review the full suite of documents available from GrantConnect, the Australian Government grants information system and:

NHMRC

UQ